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Messages - SarahVaughter

Infadolan does not contain a sunscreen and you should apply a sunscreen prior to Infadolan if you apply it in the morning.


  All Retinoids make the skin more sun sensitive but the amount of vit. A in each Infadolan application is not high enough to warrant sun sensitivity concern.  From my own experience, I do notice sun sensitivity after applying Tretinoin (Retinoic acid) 0.025% but not after applying Infadolan.


  Infadolan is a protective ointment and due to its oiliness it is not very suitable to be applied dally, except for dry areas such as the top of hands, around the eyes or on the lips.


  Some of our customers actually do apply a little Infadolan on their face daily after shaving.


  Tretinoin in many cases normalizes the distribution of skin pigment melanin and thus helps diminishing pigmentations; nevertheless it makes the skin more sensitive to the sun. There is however no ideal and completely side-effect-free substance that helps with hyper-pigmentation.

Dermarolling / Microneedling / Hyperpigmentation - Acne
« on: March 08, 2012, 02:37:53 PM »
Shipping takes about two weeks to Malaysia, but it can take even longer.

   What kind of permanent side effect did you get from Accutane?


  From our dermarolling instructions:


  "When taking Accutane: You should wait with dermarolling and single-needling for at least six months after taking the last dose of Accutane. Then, always do a small test patch first to see how it heals".


  From our forum:


Tretinoin is not the same as Accutane. And in addition, Accutane is taken orally.


  Tretinoin often dries out the skin, especially initially before the skin gets used to it. Applying too much or too frequently may result in red, itching skin (fully reversible).


  Tretinoin is very useful in certain skin condition but the more is not the better.

Dermarolling / Microneedling / Acne Scars
« on: March 08, 2012, 01:42:11 PM »
Yes, 500 / 5 = 1%.

Due to the shape of your hypopigmentation, I'd say buy a 1.5 mm dermastamp. Do not insert the full length of the needles into the skin. Stamp densely every two weeks.

   The single needle instrument is even better for your shape of hypopigmentation but the lower calf area is perhaps quite painful for single needling. If you decide to use the single needles, needle the hypopigmented patches and slightly outside of its borders to enable migration of the melanocytes from the surrounding normal skin into the hypo-pigmented areas.

When you complete several needlings, expose your scars to the sun because melanin pigment is produced as a reaction to UV (provided there are melanocyte cells in the area to produce it).               

Consider buying a NB-UVB lamp.
More about it in my reply #13 in this forum thread:


 Related posting:

Dermarolling / Microneedling / Kelo-cote cream for hypertrophic scars
« on: March 07, 2012, 05:49:18 PM »
There is almost no metabolic activity in old/mature scars. Needling can induce some activity and trigger revascularization, melanocyte production etc.


  I cannot answer whether a needled scar will react in the same way as a new scar. All I can say is that it the fight to improve scars, you have to improvise a little and try different approaches. If needling itself doesn't improve the scar, try needling + silicone sheets, needling + Tretinoin etc. until some combination will hopefully work.

Dermarolling / Microneedling / Acne Scars
« on: March 07, 2012, 05:31:42 PM »
10 g of cloramine-T in one litre of water is a 1% solution not a 0.1 % solution. A 0.1% solution is not strong enough for disinfection, for that you need at least 0.5% for 8 hours overnight.

A 2% solution is made with 20 grams in 1 litre of water.

  A 1% solution is made with 20 grams in 2 litre of water. (or 10 grams in 1 litre, etc.) A 0.5% solution is made with 20 grams in 4 litres/1 gallon of water. (or 10 grams in 2 litres/half a gallon etc.)

   I tried it on my scale and 10 g is roughly 4 flat teaspoons.


Yes, you can roll and stamp the same day.  

  Infadolan is mainly for > 0.5 mm aftercare because the deeper you needle the more protection the skin needs afterwards. Itnfadolan can be applied after any size roller though.


  If you are acne prone, do not apply Infadolan after rolling with a 0.5 mm.

  Apply it only after your dermastamping session.

Depression is a very serious illness and inflicting physical pain to oneself sometimes helps relieving the unbearable mental pain.

   The skin on the inside of the arm is relatively thin and sensitive. I think a regular 1 mm roller is suitable. Roll densely every 10 days. After rolling, perform pressure massage on your raised scars. The massage is described here:


    There is no problem combining it with tattoo removal, just stop rolling about five days prior to the tattoo removal.


  Concerning the scars on your thigh and calves, I recommend a 1.5 mm dermastamp. You can use the dermastamp on your arms as well but do not insert the needles fully.


  You are right, there is currently no method that can completely remove a deep scar but it is possible to improve their appearance and the type of your scars usually responds well to long-term dermarolling.


  BTW, dermarolling may diminish your tattoo a little:

Dermarolling / Microneedling / Hyperpigmentation - Acne
« on: March 07, 2012, 04:25:59 AM »
Dermarolling is very often successful in diminishing post-acne hyperpigmentation because it speeds up the turnover of the skin.


  Buy a 0.5 mm regular roller and roll about 2-3 times a week.


  Tretinoin cream (A-Ret) 0.025% is also useful in your case.

Dermarolling / Microneedling / Stretch Marks - individual needling
« on: March 06, 2012, 10:14:39 AM »


  Week 1:

Day 1 - dry brushing, vit. C application (as explained in our instructions)

Day 2 - apply Tretinoin (A-Ret)

Day 3 - dry brushing, vit. C application

Day 4 - apply Tretinoin

Day 5 - apply nothing. Give your skin a break

Day 6 - dry brushing, vit. C application

Day 7 - apply Tretinoin

(If the skin gets too irritated, reduce the frequency of applications)

 Tretinoin cannot be used when pregnant, planning a pregnancy or while breastfeeding.

Week 2:

-Do the same routine as in week 1 until the rolling day. Roll the stretch mark (the whole area) with a regular roller on the day it suits you the best. Roll them densely with a regular roller. Apply Infadolan immediately after. Continue applying Infadolan for at least five more days.

During the next four weeks, use the single needle or a dermastamp or a ONE LINER dermaroller (roll thoroughly and densely) on the individual stretch marks until they are all done. You can for example thoroughly single needle/roll every day five stretch marks (every day different ones) until they are all done.


  Right after needling/one liner rolling, massage some Tretinoin (A-Ret) into the individual stretch marks. First do a small test patch to see how your skin reacts to it. Apply Infadolan on top of Tretinoin.


 You should complete the single needling, stamping  or one liner rolling of all your stretch marks within four weeks. Give your skin a one-week break and restart the whole process. This time, apply vit. C for 4 consecutive days, roll the whole area with a regular roller, and then during the next four weeks use the single needle or a dermastamp or a one liner dermaroller on each individual stretchmark.


  The weeks in between dermarolling with a regular roller: keep the dermarolled area moisturized, apply vit. C and Tretinoin at least twice a week. Do not apply both the same day.


 After about four full sessions, give your skin a one-month break. Then restart again.


Why Tretinoin:

Related subject:

Psychological aspects of stretch marks:

If you have just a few stretch marks, treat them all in one session (every 4-5 weeks). First, use a 1.5 mm dermastamp on each individual stretch mark: stamp each stretch mark very densely. After you will have stamped all of them, roll the entire area with your regular 1.5 mm dermaroller.

If you have too many stretch marks to treat them thoroughly and densely in a single session, you have to spread it out over multiple treatments. In this case you should do it the other way round. First, roll the entire area with your regular 1.5 mm dermaroller (every 4-5 weeks). When the redness is gone (in a few days) and you can see clearly the individual stretch marks, stamp each individual stretch mark densely. Stamp every day (or so) a few stretch marks, until they are all done.

The reason I introduced this "spread out" treatment is that I recommend combining stamping/needling and rolling. Needling and stamping is very laborious and it must be done thoroughly and densely. Nearly noone has the time to do all stretch marks in one session.

Dermarolling / Microneedling / Vitamin C caused a burn :(
« on: March 04, 2012, 05:22:26 PM »
OK . I am sorry about that. I will change the instructions regarding vit. C application after single needling. Waiting 24 hours is not enough in some cases. It is OK after dermarolling but single needling is denser and deeper and the skin can still be a bit "raw" 24 hours later.


  Acidic forms of vitamins are the most potent but also the most irritating. There should be however no problem if you apply vit. C on healed skin.

   Do not worry, it is only temporary and it will heal OK. Keep the skin moisturized.

   Unfortunately, there is no skin-lightening product that is 100% problem-free.

Dermarolling / Microneedling / Where to get EMLA / numbing cream?
« on: March 04, 2012, 12:10:19 PM »

Dermarolling / Microneedling / Vitamin C caused a burn :(
« on: March 04, 2012, 10:27:26 AM »
Did you use 4 parts of vit. C to 19 parts of water?

Then instead of being cautious, you were extremely brazen because that is a concentration of 21% instead of the 5% we recommend to start with.

If you intended to be overcautious, you should have used even less initially, like 2%.

21% is a huge concentration, very acidic..

I am sorry it happened to you though - hopefully the effect is temporary (I think so, it's just vit. C after all.)

Dermarolling / Microneedling / need help for nightly routine
« on: March 03, 2012, 04:55:34 PM »
Try this routine, but without applying anything in the morning (if you have no time). Everything is applied in the evening. The routine is explained below the sentence:


  "An example of a daily routine for acne prone, scarred, pigmented or aged/damaged skin (can be of course altered in a way to suit you better)"

Tyrosine is water-soluble, but very little. You should use Phenylalanine instead. It is more water-soluble and it is converted to tyrosine.


  As I already said, Vitiligo is hypopigmented skin but it is not a scar. There is very little metabolic activity in scar tissue and what works for vitiligo doesn’t automatically work for scar tissue.


  In the studies below, they targeted just the hypopigmentated area by UVA radiation.  

  Unfortunately you do not have the equipment to do targeted, intensive UV exposure, so you have to expose the entire area to the sun. Apply a high factor sunscreen on the skin all around the scar to prevent darkening of the skin that surrounds the scar.


Phenylalanine and UVA light for the treatment of vitiligo

  R. H. Cormane, A. H. Siddiqui, W. Westerhof and R. B. H. Schutgens

  The administration of phenylalanine (Phe) combined with UVA exposure was found to be effective in vitiligo. Phe is an amino acid which constitutes part of the daily dietary protein, and when orally administered in a dose of 50 mg/kg body weight, it results in an elevated plasma level. Since peak concentrations of Phe in the blood are reached between 30 and 45 min after ingestion, UVA exposure was administered at this time. After 4 months (32 treatments) reasonable repigmentation preferentially occurred in the skin area of subcutaneous fat (adipose tissue). Apart from the repigmentation of hypopigmented macules, vitiligo patients can tolerate more sun than usual, especially at the vitiliginous lesion, and they experience no sunburn as a result of Phe-UVA therapy. Normal skin also tans very well



  Vitiligo Therapy with Oral and Topical Phenylalanine with UVA Exposure

  C. Antoniou M.D.*, H. Schulpis M.D., T. Michas M.D., A. Katsambas M.D., N. Frajis B.S., S. Tsagaraki M.D., J. Stratigos M.D.



  ABSTRACT: The administration of phenylalanine (Phe) combined with UVA exposure was found to be effective in treating vitiligo. Twenty-one patients with vitiligo were divided in two groups: eleven patients were treated with oral L-Phe in a dose of 100 mg/kg body weight and with UVA exposure and ten patients were treated with oral L-Phe in a dose of 100 mg/kg body weight and with UVA exposure. In addition, in the second group, a cream containing 10% L-Phe was applied to the vitiliginous areas. The best -+results occurred in the second group. No side effects were found in either group.



  L-Phenylalanine and UVA Irradiation in the Treatment of Vitiligo

Siddiqui AH, Stolk L·ML, Bhaggoe R, Hu R, Schutgens RBH, Westerhof W

Dermatology 1994;188:215–218 (DOI: 10.1159/000247142)



In order to evaluate the efficacy of L-phenylalanine (L-Phe) in combination with UVA therapy for vitiligo an open trial (149 patients, 18 months) and a small double-blind trial (32 patients, 6 months) were conducted. Oral L-Phe loading resulted in peak plasma levels of L-Phe after 30–60 min and a slight increase in the plasma tyrosine level. Response to L-Phe plus UVA irradiation was positive, and various grades of repigmentation not exceeding 77% in the open and 60% in the blind trial were observed. An increased L-Phe dose resulted in increased L-Phe plasma levels but not in improved clinical results. The optimal L-Phe dose appears to be lower than 50 mg/kg/day. Although it is difficult to draw firm conclusions from the present investigation, we think that L-Phe may have a place in the treatment of vitiligo and its role merits further investigation.

Dermarolling / Microneedling / ACNE SCARS
« on: March 01, 2012, 01:17:28 PM »
The dermastamps are now waiting in customs. This can take one day but it can also take two weeks..