Dermarolling / Microneedling / Any other recommendations for skin creams / vitamin E?
« on: February 08, 2012, 08:20:11 AM »Concerning vit. E:
https://http://scholar.googleusercontent.com/scholar?q=cache:2n35NMFTs6oJ:scholar.google.com
Vitamin E
The role of vitamin E (a-tocopherol) in wound
healing is controversial, because possesses positive
and negative effects. Vitamin E is a known antiox-
idant that has anti-inflammatory properties. It alters
prostaglandin production by inhibiting phospholipase
A2 activity, resulting in decreased collagen produc-
tion and decreased inflammation. Most authors agree
that high doses of vitamin E lead to delayed wound
healing [25]. For cutaneous wounds, topical vitamin E
appears to offer no cosmetic benefit and its applica-
tion may actually be detrimental [26].
For diabetics, vitamin E may offer some benefit in
wound healing. Two studies [27,28] using diabetic
mice models have shown improvement in wound
healing using vitamin E, by a proposed mechanism
of inhibition of lipid peroxidation. Although the exact
role of vitamin E in wound healing is not understood,
it appears to involve cell differentiation, epithelializa-
tion, cell-mediated immunity, the early inflammatory
response, and angiogenesis [29,30]
However, the results of studies concerning vit. E and would healing are inconsistent.